EN1 anticorps (AA 351-392) (Biotin)

N° du produit ABIN1393069

Détail du produit anti-EN1 anticorps (Biotin)

Antigène: EN1 (Engrailed Homeobox 1 (EN1))

Épitope: AA 351-392

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EN1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human EN1/Engrailed 1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur EN1

Antigène: EN1 (Engrailed Homeobox 1 (EN1))

Autre désignation: EN1/Engrailed 1 (EN1 Produits)

Synonymes: anticorps EN1, anticorps En-1, anticorps Mo-en.1, anticorps ENG-1, anticorps en-1, anticorps en1, anticorps eng1, anticorps zgc:100771, anticorps en1-A, anticorps engrailed-1, anticorps xen1, anticorps Gg-En-1, anticorps en-3, anticorps engrailed, anticorps engrailed homeobox 1, anticorps engrailed 1, anticorps engrailed homeobox 1a, anticorps engrailed homeobox 1 S homeolog, anticorps EN1, anticorps En1, anticorps en1a, anticorps en1.S

Sujet:

Synonyms: En 1, EN1, Engrailed 1, Engrailed, Engrailed homeobox 1, Engrailed homolog 1, HME1_HUMAN, Homeobox protein en-1, Homeobox protein engrailed 1, Homeobox protein engrailed-1, Hu-En-1, Mo-en.1.

Background: The engrailed-1 gene, EN1, a murine homolog of the Drosophila homeobox gene engrailed (EN), is required for midbrain and cerebellum development and dorsal/ventral patterning of the limbs as well as apical ectodermal ridge formation. In Drosophila, the EN gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Human EN-1 and EN-2 are homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. Different mutations in the mouse homo-logs, EN-1 and EN-2, produce different developmental defects that frequently are lethal. EN-1 is highly expressed by essentially all dopaminergic neurons in the substantia nigra and ventral tegmentum. EN-1 and EN-2 regulate expres-sion of a-synuclein, a gene that is genetically linked to Parkinson?s disease.

ID gène: 2019

UniProt: Q05925

Pathways: Dopaminergic Neurogenesis