GPR143 anticorps (AA 201-300) (Biotin)

N° du produit ABIN1393345

Détail du produit anti-GPR143 anticorps (Biotin)

Antigène: GPR143 (G Protein-Coupled Receptor 143 (GPR143))

Épitope: AA 201-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPR143 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human OA1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur GPR143

Antigène: GPR143 (G Protein-Coupled Receptor 143 (GPR143))

Autre désignation: OA1/GPR143 (GPR143 Produits)

Synonymes: anticorps NYS6, anticorps OA1, anticorps Oa1, anticorps RGD1565799, anticorps G protein-coupled receptor 143, anticorps GPR143, anticorps Gpr143

Sujet:

Synonyms: ALBINISM OCULAR TYPE I, G protein coupled receptor 143, G-protein coupled receptor 143, GP143_HUMAN, GPR143, MOA1, NETTLESHIP FALLS TYPE OCULAR ALBINISM, Ocular albinism type 1 protein, Ocular albinism type 1 protein homolog, Ocular albinism1 Nettleship Falls type.

Background: G protein-coupled receptors (GPRs or GPCRs), are members of the largest protein family and play a role in many different stimulus-response pathways. G-protein coupled receptors mediate extracellular signals into intracellular signals (G-protein activation). They respond to a great variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GPR143, also designated ocular albinism type 1 protein (OA1), is detected exclusively in pigment cells. OA1, which is a multi-pass membrane protein, is a melanosomal protein expressed primarily in pigment cells. Defects in the gene encoding for OA1 cause ocular albinism, an X-linked disorder mainly characterized by retinal hypopigmentation and visual impairment.