BRWD3 anticorps (AA 1701-1802) (Biotin)

N° du produit ABIN1393465

Détail du produit anti-BRWD3 anticorps (Biotin)

Antigène: BRWD3 (Bromodomain and WD Repeat Domain Containing 3 (BRWD3))

Épitope: AA 1701-1802

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRWD3 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human BRWD3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur BRWD3

Antigène: BRWD3 (Bromodomain and WD Repeat Domain Containing 3 (BRWD3))

Autre désignation: BRWD3 (BRWD3 Produits)

Synonymes: anticorps CG18670, anticorps CG31132, anticorps CG6400, anticorps Dmel\\CG31132, anticorps anon-WO0118547.520, anticorps anon-WO0118547.620, anticorps dBRWD3, anticorps l(3)05842, anticorps l(3)s5349, anticorps ram, anticorps BRODL, anticorps MRX93, anticorps Brodl, anticorps D030064D06Rik, anticorps Gm596, anticorps RGD1559445, anticorps bromodomain and WD repeat domain containing 3, anticorps CG31132 gene product from transcript CG31132-RA, anticorps PH-interacting protein, anticorps BRWD3, anticorps LOC412406, anticorps Brwd3

Sujet:

Synonyms: BRODL, Bromo domain containing protein disrupted in leukemia, Bromodomain and WD repeat domain containing 3, Novel WD repeat domain protein, BRWD3_HUMAN.

Background: Members of the WD repeat protein family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis and gene regulation. BRWD3 (bromodomain and WD repeat-containing protein 3) is a 1,802 amino acid protein expressed in fetal liver and most adult tissues. Existing as five alternatively spliced isoforms, BRWD3 contains two bromo domains, nine WD repeats and is thought to play a role in transcription by modifying chromatin. Mutations in the gene encoding BRWD3 are the cause of mental retardation X-linked type 93 (MRX93), which is also known as mental retardation X-linked with macrocephaly (XLMR). MRX93 is characterized by mild intellectual disability, macrocephaly, a prominent forehead and large cupped ears.