FEZ2 anticorps (AA 165-240) (AbBy Fluor® 647)
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- Antigène Voir toutes FEZ2 Anticorps
- FEZ2 (Fasciculation and Elongation Protein zeta 2 (Zygin II) (FEZ2))
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Épitope
- AA 165-240
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Reactivité
- Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FEZ2 est conjugé à/à la AbBy Fluor® 647
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Souris, Rat
- Homologie
- Human,Cow,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human FEZ2/Zygin2
- Isotype
- IgG
- Top Product
- Discover our top product FEZ2 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- FEZ2 (Fasciculation and Elongation Protein zeta 2 (Zygin II) (FEZ2))
- Autre désignation
- FEZ2/Zygin2 (FEZ2 Produits)
- Synonymes
- anticorps HUM3CL, anticorps 9030616F16, anticorps D17Ertd315e, anticorps Zrp, anticorps fasciculation and elongation protein zeta 2, anticorps fasciculation and elongation protein zeta 2 (zygin II), anticorps FEZ2, anticorps Fez2
- Sujet
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Synonyms: Fasciculation and elongation protein zeta 2, Fasciculation and elongation protein zeta-2 , FEZ 2, Fez2, FEZ2_HUMAN, Highly similar to zyginII, HUM3CL, MGC117372, Pre T/NK cell associated protein, Zygin 2, Zygin II, Zygin-2.
Background: Zygin 2 is a 353 amino acid cytoplasmic protein that belongs to the zygin family. Zygin 2 is found as a difulfide-linked homodimer but may for heterodimers with FEZ1. the plasma membrane to the cytoplasm by activation of PKC zeta. PKC zeta also enhances zygin 1 interaction with UFD2 and polyubiquitination. Expressed mainly in brain, zygin 1 is a mammalian ortholog of Caenorhabditis elegans UNC-76 and is able to restore partial locomotion and axonal fasciculation to C. elegans UNC-76 mutants, which suggest a functional role in axonal outgrowth. As component of the network of molecules that regulate cellular morphology and axon guidance machinery, zygin 1 may also be involved in microtubule associated transport and transcriptional regulation. Mutations in the gene encoding zygin 1 may be linked to the pathogenesis of schizophrenia. Zygin 1 exists as two alternatively spliced isoforms that are designated isoform long and isoform short.
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