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KALRN anticorps (AA 1401-1500) (Biotin)

KALRN Reactivité: Humain ELISA, IHC (fro), IHC (p) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1393759
  • Antigène Voir toutes KALRN Anticorps
    KALRN (Kalirin, RhoGEF Kinase (KALRN))
    Épitope
    • 14
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    AA 1401-1500
    Reactivité
    • 34
    • 13
    • 13
    • 1
    Humain
    Hôte
    • 33
    • 1
    Lapin
    Clonalité
    • 34
    Polyclonal
    Conjugué
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KALRN est conjugé à/à la Biotin
    Application
    • 13
    • 13
    • 11
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Human,Mouse,Rat,Dog,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human KALRN/Duo
    Isotype
    IgG
    Top Product
    Discover our top product KALRN Anticorps primaire
  • Indications d'application
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    KALRN (Kalirin, RhoGEF Kinase (KALRN))
    Autre désignation
    KALRN/Duo (KALRN Produits)
    Synonymes
    anticorps ARHGEF24, anticorps CHD5, anticorps CHDS5, anticorps DUET, anticorps DUO, anticorps HAPIP, anticorps TRAD, anticorps KALRN, anticorps 2210407G14Rik, anticorps AV235988, anticorps E530005C20Rik, anticorps Gm539, anticorps Hapip, anticorps Duo, anticorps Kalirin, anticorps kalirin RhoGEF kinase, anticorps kalirin, RhoGEF kinase, anticorps kalirin, anticorps kalirin RhoGEF kinase L homeolog, anticorps putative kalirin, anticorps KALRN, anticorps LOC460643, anticorps Kalrn, anticorps kalrn, anticorps kalrn.L, anticorps LOC100473997, anticorps Smp_162970
    Sujet

    Synonyms: Duo, FLJ16443, HAPIP, Huntingtin associated protein interacting protein duo , Huntingtin-associated protein-interacting protein, Kalirin isoform 2, Kalirin, KALRN , KALRN_HUMAN , Protein Duo, RhoGEF kinase, Serine/threonine kinase with Dbl and pleckstrin homology domains , Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain, TRAD.

    Background: HAP1 (huntingtin-associated protein 1) binds to huntingtin (1). Huntingtin is a protein that contains a polyglutamine region and when the number of glutamine repeats exceeds 35, the gene encodes a version of huntingtin that leads to Huntington?s disease (HD) (2,3). The ability of HAP1 to bind to huntingtin is enhanced by an expanded polyglutamine repeat region (1). HAP1 shows neuronal localization and moves with huntingtin in nerve fibers (4,5). HAP1 is primarily expressed in brain tissue, with greater expression in the olfactory bulb and brain stem (1). Mouse HAP1 is localized to membrane-bound organelles including large endosomes, tubulovesicular structures and budding vesicles in neurons (6). Duo, also designated huntingtin-associated protein interacting protein or HAPIP, binds Huntingtin-associated protein 1 (HAP1) and may have a role in vesicle trafficking and cytoskeletal function.

    Pathways
    Neurotrophin Signaling Pathway
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