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KIAA0319 anticorps (AA 682-760) (AbBy Fluor® 555)

KIAA0319 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 555
N° du produit ABIN1393763
  • Antigène Voir toutes KIAA0319 Anticorps
    KIAA0319
    Épitope
    • 14
    • 4
    • 2
    • 2
    • 1
    • 1
    AA 682-760
    Reactivité
    • 29
    • 8
    • 6
    • 5
    • 4
    • 2
    Humain
    Hôte
    • 28
    • 2
    Lapin
    Clonalité
    • 30
    Polyclonal
    Conjugué
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KIAA0319 est conjugé à/à la AbBy Fluor® 555
    Application
    • 24
    • 12
    • 12
    • 10
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human DYX2/KIAA0319
    Isotype
    IgG
    Top Product
    Discover our top product KIAA0319 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    KIAA0319
    Autre désignation
    DYX2/KIAA0319 (KIAA0319 Produits)
    Synonymes
    anticorps DYLX2, anticorps DYX2, anticorps 4930451E12Rik, anticorps Kiaa0319, anticorps KIAA0319, anticorps RIKEN cDNA D130043K22 gene, anticorps KIAA0319 ortholog, anticorps similar to mKIAA0319 protein, anticorps KIAA0319, anticorps D130043K22Rik, anticorps RGD1307443
    Sujet

    Synonyms: DLX 2, DLX2, DYLX 2, DYLX2, Dyslexia susceptibility 2, Dyslexia-associated protein KIAA0319 DYX 2, DYX2, K0319_HUMAN, Kiaa0319, MGC176717.

    Background: DYX2 is a 1072 amino acid single-pass transmembrane protein that contains one MANSC domain and two PKD (Polycystic Kidney Disease) domains, which are usually found in the extracellular regions of proteins and are involved in protein-protein interactions. In DYX2, it is likely that its PKD domains mediate the interaction between neurons and glial fibers during neuronal migration. When overexpressed, this plasma membrane protein colocalizes with EEA1 (early endosome antigen 1) in large intracellular vesicles, suggesting that it is endocytosed and recycled. DYX2 is highly expressed in brain cortex, cerebellum, amygdala, putamen and hippocampus. Defects in the gene encoding DYX2 may be the cause of dyslexia type 2, a relatively common disorder that is characterized by reading performance impairment in the absence of sensory or neurologic disability. There are three isoforms of DYX2 that are produced as a result of alternative splicing events

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