LMCD1 anticorps (AA 51-160) (Biotin)

N° du produit ABIN1393837

Détail du produit anti-LMCD1 anticorps (Biotin)

Antigène: LMCD1 (LIM and Cysteine-Rich Domains 1 (LMCD1))

Épitope: AA 51-160

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LMCD1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human LMCD1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur LMCD1

Antigène: LMCD1 (LIM and Cysteine-Rich Domains 1 (LMCD1))

Autre désignation: LMCD1 (LMCD1 Produits)

Synonymes: anticorps LMCD1, anticorps AW455500, anticorps AW553074, anticorps dyxin, anticorps LIM and cysteine rich domains 1, anticorps LIM and cysteine-rich domains 1, anticorps LMCD1, anticorps lmcd1, anticorps Lmcd1

Sujet:

Synonyms: Dyxin, LIM and cysteine rich domains 1, LIM and cysteine rich domains protein 1, LIM and cysteine-rich domains protein 1, LMCD1_HUMAN.

Background: Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T cells signaling pathway.