MAP3K4 anticorps (AA 1351-1450) (Biotin)

N° du produit ABIN1393891

Détail du produit anti-MAP3K4 anticorps (Biotin)

Antigène: MAP3K4 (Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4))

Épitope: AA 1351-1450

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K4 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MAP3K4/MEK kinase-4

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur MAP3K4

Antigène: MAP3K4 (Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4))

Autre désignation: MAP3K4/MEK kinase-4 (MAP3K4 Produits)

Synonymes: anticorps MAPKKK4, anticorps MEKK4, anticorps MTK1, anticorps PRO0412, anticorps D17Rp17, anticorps D17Rp17e, anticorps MEKK 4, anticorps Mek4b, anticorps Mekk4, anticorps RP17, anticorps Rp17a, anticorps Tas, anticorps mKIAA0213, anticorps mitogen activated protein kinase kinase kinase 4, anticorps mitogen-activated protein kinase kinase kinase 4, anticorps Map3k4, anticorps MAP3K4

Sujet:

Synonyms: FLJ42439, KIAA0213, M3K4_HUMAN, MAP three kinase 1, MAP3K4, MAPK/ERK kinase kinase 4, MAPKKK4 antibodyMEK kinase 4, MEKK 4, MEKK4, Mitogen-activated protein kinase kinase kinase 4, MTK1, PRO0412, RP3-473J16.4

Background: Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli including growth factors. The MEK kinases (also designated MAP kinase kinase kinases, MKKKs, MAP3Ks or MEKKs) phosphorylate and thereby activate the MEKs (also called MAP kinase kinases or MKKs), including ERK, JNK and p38. These activated MEKs in turn phosphorylate and activate the MAP kinases. The MEK kinases include Raf-1, Raf-B, Mos, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4, ASK 1 (MEK kinase-5) and MAP3K6 (MEK kinase-6). MEK kinase-1 has been shown to phosphorylate MEK-1 via Raf-independent pathway. Evidence suggests that MEK-3 is preferentially activated by MEK kinase-3 and that MEK-4 is activated by both MEK kinase-2 and MEK kinase-3. MEK kinase-4 has been shown to specifically activate the JNK path-way. ASK1 activates both MEK-4 and MEK-3/MEK-6 pathways.

Pathways: Signalisation MAPK