MTPN anticorps (AA 41-118) (Biotin)

N° du produit ABIN1393939

Détail du produit anti-MTPN anticorps (Biotin)

Antigène: MTPN (Myotrophin (MTPN))

Épitope: AA 41-118

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTPN est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Myotrophin/GCDP

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur MTPN

Antigène: MTPN (Myotrophin (MTPN))

Autre désignation: Myotrophin/GCDP (MTPN Produits)

Synonymes: anticorps MGC76285, anticorps GCDP, anticorps V-1, anticorps Gcdp, anticorps wu:fa10f07, anticorps zgc:64078, anticorps 5033418D15Rik, anticorps V1, anticorps myotrophin, anticorps myotrophin S homeolog, anticorps mtpn, anticorps MTPN, anticorps Mtpn, anticorps mtpn.S

Sujet:

Synonyms: FLJ31098, FLJ99857, GCDP, Granule cell dferentiation protein, MTPN, MTPN_HUMAN, Myotrophin, Protein V 1, Protein V-1, V 1, MTPN_HUMAN.

Background: Myotrophin (V-1 protein) is a ubiquitously expressed cytoplasmic protein that can translocate to the nucleus during sustained NFkB activation. The gene encoding for this protein localizes to chromosome 7q33. Myotrophin may be involved in cerebellar morphogenesis and contains an acetylated N-terminus and 2.5 internal 33 amino acid ankyrin repeats. It is important in the differentiation of cerebellar neurons, particularly of granule cells. The 117 amino acid protein has been associated with, and able to induce, cardiac hypertrophy. Myotrophin increases protooncogene, ANF and Beta-Myosin heavy chain transcript levels. Myotrophin is upregulated when myocytes undergo cyclic stretch or are treated with tumor necrosis factor Alpha (TNF Alpha) or interleukin-1Beta. Highest levels of Myotrophin are detected in brain and lowest levels in skeletal muscle.