NELL2 anticorps (AA 201-300) (Biotin)

N° du produit ABIN1393963

Détail du produit anti-NELL2 anticorps (Biotin)

Antigène: NELL2 (NEL-Like 2 (Chicken) (NELL2))

Épitope: AA 201-300

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NELL2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NELL2/NRP2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur NELL2

Antigène: NELL2 (NEL-Like 2 (Chicken) (NELL2))

Autre désignation: NELL2/NRP2 (NELL2 Produits)

Synonymes: anticorps A330108N19Rik, anticorps R75516, anticorps mel91, anticorps nel, anticorps NRP2, anticorps nell2, anticorps wu:fj43h11, anticorps zgc:158375, anticorps neural EGFL like 2 L homeolog, anticorps NEL-like 2, anticorps neural EGFL like 2, anticorps neural EGFL like 2a, anticorps nell2.L, anticorps Nell2, anticorps NELL2, anticorps nell2a

Sujet:

Synonyms: A330108N19Rik, Mel91, MEL91 protein, NEL like 2 chicken, NEL-like protein 2, Nel-related protein 2, NELL2, NELL2_HUMAN, NRP2, Protein kinase C-binding protein NELL2, R75516.

Background: NELL2 is a secreted glycoprotein with one N-terminal TSP-like domain, five VWFC (von Willebrand factor C) domains and six EGF-like repeats that participate in calcium binding. NELL2 exists as a homotrimer associated with the endoplasmic reticulum (ER) and is specifically expressed in neurons playing a role in calcium-dependent intracellular events. NELL2 may act as a trophic factor in addition to its role as a signaling molecule implicated in the regulation of cell growth and differentiation. Due to alternative splicing, an additional NELL2 isoform exists that is identical to full length NELL2 except that it lacks the signal peptide that directs secretion. The additional isoform is therefore retained in the cytosol and functions as a non-secreted cytoplasmic protein that interacts with PKC bI.