Chromosome 12 Open Reading Frame 52 (C12orf52) (AA 51-150) anticorps (AbBy Fluor® 488)
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- Antigène Voir toutes Chromosome 12 Open Reading Frame 52 (C12orf52) Anticorps
- Chromosome 12 Open Reading Frame 52 (C12orf52)
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Épitope
- AA 51-150
- Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- AbBy Fluor® 488
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Cow,Sheep
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human RITA/C12orf52
- Isotype
- IgG
- Top Product
- Discover our top product C12orf52 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- Chromosome 12 Open Reading Frame 52 (C12orf52)
- Autre désignation
- RITA/C12orf52 (C12orf52 Produits)
- Synonymes
- anticorps RITA, anticorps C12orf52, anticorps AI853657, anticorps C86297, anticorps Rita, anticorps RBPJ interacting and tubulin associated 1, anticorps RBPJ interacting and tubulin associated 1 L homeolog, anticorps RITA1, anticorps rita1.L, anticorps Rita1
- Sujet
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Synonyms: C12orf52, Chromosome 12 open reading frame 52, RBPJ-interacting and tubulin-associated protein, RITA, RITA_HUMAN.
Background: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf52 gene product has been provisionally designated C12orf52 pending further characterization.
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