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Chromosome 12 Open Reading Frame 52 (C12orf52) (AA 51-150) anticorps (Biotin)

C12orf52 Reactivité: Humain ELISA, IHC (fro), IHC (p) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1394245
  • Antigène Voir toutes Chromosome 12 Open Reading Frame 52 (C12orf52) Anticorps
    Chromosome 12 Open Reading Frame 52 (C12orf52)
    Épitope
    • 14
    • 8
    • 8
    • 7
    AA 51-150
    Reactivité
    Humain
    Hôte
    • 29
    Lapin
    Clonalité
    • 29
    Polyclonal
    Conjugué
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Biotin
    Application
    • 15
    • 14
    • 13
    • 13
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Human,Cow,Sheep
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human RITA/C12orf52
    Isotype
    IgG
    Top Product
    Discover our top product C12orf52 Anticorps primaire
  • Indications d'application
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    Chromosome 12 Open Reading Frame 52 (C12orf52)
    Autre désignation
    RITA/C12orf52 (C12orf52 Produits)
    Synonymes
    anticorps RITA, anticorps C12orf52, anticorps AI853657, anticorps C86297, anticorps Rita, anticorps RBPJ interacting and tubulin associated 1, anticorps RBPJ interacting and tubulin associated 1 L homeolog, anticorps RITA1, anticorps rita1.L, anticorps Rita1
    Sujet

    Synonyms: C12orf52, Chromosome 12 open reading frame 52, RBPJ-interacting and tubulin-associated protein, RITA, RITA_HUMAN.

    Background: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf52 gene product has been provisionally designated C12orf52 pending further characterization.

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