SLC25A12 anticorps (AA 101-200) (Biotin)
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- Antigène Voir toutes SLC25A12 (Slc25a12) Anticorps
- SLC25A12 (Slc25a12) (Solute Carrier Family 25 (Mitochondrial Carrier, Aralar), Member 12 (Slc25a12))
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Épitope
- AA 101-200
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SLC25A12 est conjugé à/à la Biotin
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Souris
- Homologie
- Human,Rat,Dog,Cow,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human SLC25A12/ARALAR
- Isotype
- IgG
- Top Product
- Discover our top product Slc25a12 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- SLC25A12 (Slc25a12) (Solute Carrier Family 25 (Mitochondrial Carrier, Aralar), Member 12 (Slc25a12))
- Autre désignation
- SLC25A12/ARALAR (Slc25a12 Produits)
- Synonymes
- anticorps cb929, anticorps cb1094, anticorps zgc:66248, anticorps wu:fj94c07, anticorps AGC1, anticorps ARALAR, anticorps Aralar1, anticorps RGD1561141, anticorps ARALAR1, anticorps 2610002D09Rik, anticorps AI839531, anticorps B230107K20Rik, anticorps BB129864, anticorps solute carrier family 25 (aspartate/glutamate carrier), member 12, anticorps solute carrier family 25 member 12, anticorps solute carrier family 25 member 12 L homeolog, anticorps solute carrier family 25 (mitochondrial carrier, Aralar), member 12, anticorps slc25a12, anticorps SLC25A12, anticorps slc25a12.L, anticorps Slc25a12
- Sujet
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Synonyms: AGC1, Araceli hiperlarga, ARALAR, ARALAR1, Calcium binding mitochondrial carrier superfamily member, Calcium-binding mitochondrial carrier protein Aralar1, CMC1_HUMAN, Mitochondrial aspartate glutamate carrier 1, SLC25A12, Solute carrier family 25 member 12, solute carrier family 25, member 12.
Background: Calcium signaling in mitochondria is important in order for it to function in response to a variety of extracellular stimuli. Signaling begins with Ca(2+) entry in mitochondria via the Ca(2+) uniporter followed by Ca(2+) activation of three dehydrogenases in the mitochondrial matrix. ARALAR, the neuronal Ca(2+)-binding mitochondrial aspartate-glutamate carrier, has Ca(2+) binding domains facing the extramitochondrial space and functions in the malate-aspartate NADH shuttle (MAS). ARALAR is encoded by the SLC25A12 gene and is expressed in brain and skeletal muscle. ARALAR is required for the synthesis of brain aspartate and N-acetylaspartatemay and plays a role in myelin formation. It is also essential for the transmission of small Ca(2+) signals to mitochondria via an increase in mitochondrial NADH. In addition, ARALAR is implicated in conferring susceptibility to schizophrenia.
- Pathways
- Ribonucleoside Biosynthetic Process, Dicarboxylic Acid Transport
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