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SLITRK5 anticorps (AA 301-400) (FITC)

SLITRK5 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal FITC
N° du produit ABIN1394330
  • Antigène Voir toutes SLITRK5 Anticorps
    SLITRK5 (SLIT and NTRK-Like Family, Member 5 (SLITRK5))
    Épitope
    • 14
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-400
    Reactivité
    • 33
    • 11
    • 10
    • 4
    • 4
    • 4
    • 1
    • 1
    Humain
    Hôte
    • 33
    Lapin
    Clonalité
    • 33
    Polyclonal
    Conjugué
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SLITRK5 est conjugé à/à la FITC
    Application
    • 29
    • 12
    • 12
    • 12
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human SLITRK5
    Isotype
    IgG
    Top Product
    Discover our top product SLITRK5 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    SLITRK5 (SLIT and NTRK-Like Family, Member 5 (SLITRK5))
    Autre désignation
    SLITRK5 (SLITRK5 Produits)
    Synonymes
    anticorps SLITRK5, anticorps LRRC11, anticorps bA364G4.2, anticorps 2610019D03Rik, anticorps SLIT and NTRK like family member 5, anticorps SLIT and NTRK-like family, member 5, anticorps SLITRK5, anticorps slitrk5, anticorps Slitrk5
    Sujet

    Synonyms: bA364G4.2; KIAA0918; Leucine rich repeat containing 11; Leucine rich repeat containing protein 11; LRRC 11; LRRC11; SLIT and NTRK like family member 5; SLIT and NTRK like protein 5; Slit and trk like gene 5; SLITRK 5; SLIK5_HUMAN.

    Background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. SLITRK5 (SLIT and NTRK-like family, member 5), also known as LRRC11 (leucine-rich repeat-containing protein 11), is a 958 amino acid single-pass type I membrane protein that contains 16 LRR repeats and belongs to the SLITRK family. Expressed at high levels in the cerebral cortex, but also present in areas of the spinal cord and medulla, SLITRK5 functions to suppress neurite outgrowth, thereby playing a regulatory role in neuronal function. The gene encoding SLITRK5 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.

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