SPOCK1 anticorps (AbBy Fluor® 488)
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- Antigène Voir toutes SPOCK1 Anticorps
- SPOCK1 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1))
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SPOCK1 est conjugé à/à la AbBy Fluor® 488
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Application
- Western Blotting (WB)
- Réactivité croisée
- Humain
- Homologie
- Mouse,Rat,Dog,Sheep,Pig,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human SPOCK1/Testican 1
- Isotype
- IgG
- Top Product
- Discover our top product SPOCK1 Anticorps primaire
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- Indications d'application
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- SPOCK1 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1))
- Autre désignation
- Spock1/Testican 1 (SPOCK1 Produits)
- Synonymes
- anticorps SPOCK, anticorps TESTICAN, anticorps TIC1, anticorps Spock, anticorps Ticn1, anticorps testican, anticorps SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1, anticorps sparc/osteonectin, cwcv and kazal like domains proteoglycan 1, anticorps sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1, anticorps SPOCK1, anticorps Spock1
- Sujet
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Synonyms: Sparc/osteonectin, cwcv and kazal like domains proteoglycan 1, SPOCK, Testican 1, Testican1, Testican-1, TIC1, TICN1, TICN1_HUMAN.
Background: The Testican family, also designated the BM-40/SPARC/osteonectin family, is composed of highly conserved, extracellular, calcium-binding, sulfate proteoglycans. Expression of Testicans is detected in a variety of tissues, but is most abundant in brain. Family members include Testican-1, Testican-2, Testican-3 and an amino-terminal splice variant of Testican-3, designated N-Tes. Most Testicans inhibit MT-MMPs, thereby inhibiting the activity of pro-MMP-2. Testican-1 is specifically expressed in the thalamus of the brain, and is upregulated in activated astroglial cells of the cerebrum where it mediates neuronal attachment and matrix metalloproteinase activation. After a neural injury, such as a cerebral stroke, Testican-1 expression is upregulated in astrocyte cells in order to inhibit the ability of the protein Neuro-2a to form neurite extensions. Testican-1 is also a component of joint and of the growth plate cartilage that may participate in the regulation of matrix turnover.
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