GPR125 anticorps (AA 422-530) (Biotin)

N° du produit ABIN1394701

Détail du produit anti-GPR125 anticorps (Biotin)

Antigène: GPR125 (G Protein-Coupled Receptor 125 (GPR125))

Épitope: AA 422-530

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPR125 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GPR125

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur GPR125

Antigène: GPR125 (G Protein-Coupled Receptor 125 (GPR125))

Autre désignation: GPR125 (GPR125 Produits)

Synonymes: anticorps PGR21, anticorps TEM5L, anticorps 3830613O22Rik, anticorps AU044632, anticorps Tem5-like, anticorps GPR125, anticorps Gpr125, anticorps adhesion G protein-coupled receptor A3, anticorps adhesion G protein-coupled receptor A3-like, anticorps ADGRA3, anticorps Adgra3, anticorps ADGRA3L, anticorps adgra3

Sujet:

Synonyms: FLJ38547, G protein coupled receptor 125, PGR21, Probable G protein coupled receptor 125 precursor, TEM5 like, TEM5L, GP125_HUMAN, GPCR125.

Background: G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR125 (G protein-coupled receptor 125), also known as PGR21 or TEM5L, is a 1,321 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and the LN-TM7 subfamily. Considered a novel orphan adhesion-type G-protein-coupled receptor, GPR125 has five leucine rich repeats (LRR), an immunoglobulin (Ig) domain and a GPS domain. GPR125 may play a functional role in choroidal and hippocampal response to brain injury. It is also suggested that GPR125 may be a marker for spermatogonial stem cells. Four isoforms of GPR125 exists due to alternative splicing events.