TMEM132A anticorps (AA 331-430) (AbBy Fluor® 488)

N° du produit ABIN1394968

Détail du produit anti-TMEM132A anticorps (AbBy Fluor® 488)

Antigène: TMEM132A (Transmembrane Protein 132A (TMEM132A))

Épitope: AA 331-430

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM132A est conjugé à/à la AbBy Fluor® 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TMEM132A

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur TMEM132A

Antigène: TMEM132A (Transmembrane Protein 132A (TMEM132A))

Autre désignation: TMEM132A (TMEM132A Produits)

Synonymes: anticorps GBP, anticorps HSPA5BP1, anticorps 6720481D13Rik, anticorps Hspa5bp1, anticorps Orai1, anticorps R74613, anticorps Gbp, anticorps transmembrane protein 132A, anticorps TMEM132A, anticorps Tmem132a

Sujet:

Synonyms: GBP, HSPA5-binding protein 1, HSPA5BP1, T132A_HUMAN, Tmem132a, Transmembrane protein 132A.

Background: TMEM132A is a 560 amino acid protein encoded by a gene mapping to human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.