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MPDZ anticorps (AA 388-480) (AbBy Fluor® 488)

MPDZ Reactivité: Humain FACS, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 488
N° du produit ABIN1395154
  • Antigène Voir toutes MPDZ Anticorps
    MPDZ (Multiple PDZ Domain Protein (MPDZ))
    Épitope
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 388-480
    Reactivité
    • 23
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 23
    • 1
    Lapin
    Clonalité
    • 23
    • 1
    Polyclonal
    Conjugué
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MPDZ est conjugé à/à la AbBy Fluor® 488
    Application
    • 13
    • 12
    • 12
    • 9
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human MUPP1/MPDZ
    Isotype
    IgG
    Top Product
    Discover our top product MPDZ Anticorps primaire
  • Indications d'application
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    MPDZ (Multiple PDZ Domain Protein (MPDZ))
    Autre désignation
    MUPP1/MPDZ (MPDZ Produits)
    Synonymes
    anticorps HYC2, anticorps MUPP1, anticorps AI225843, anticorps B930003D11Rik, anticorps multiple PDZ domain crumbs cell polarity complex component, anticorps multiple PDZ domain protein, anticorps Multiple PDZ domain protein, anticorps inactivation-no-after-potential D protein, anticorps multiple pdz domain protein, putative, anticorps MPDZ, anticorps Mpdz, anticorps mpz-1, anticorps LOC5569990, anticorps Smp_168960
    Sujet

    Synonyms: MPDZ, Multi PDZ domain protein 1, Multi-PDZ domain protein 1, multiple PDZ domain protein, MPDZ_HUMAN.

    Background: MPDZ is a 2,042 amino acid peripheral membrane protein that colocalizes with SR-2C on the apical membrane of epithelial choroid plexus cells. Expressed in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas, MPDZ causes clustering of SR-2C, a serotonin receptor, at the cell surface. MPDZ is member of the NMDAR signaling complex that is involved in regulating AMPAR potentiation and synaptic plasticity in excitatory synapses. As a tight junction protein in epithelial cells, MPDZ interacts with SSTR3, a G-protein-coupled receptor, to regulate transepithelial permeability in a pertussis toxin sensitive manner. MPDZ, along with Kir4.2, may form a complex with other proteins in the nephron and regulate ion transport. MPDZ contains one L27 domain and thirteen PDZ domains.

    Pathways
    Synaptic Membrane, Phototransduction
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