MPDZ anticorps (AA 388-480) (AbBy Fluor® 647)
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- Antigène Voir toutes MPDZ Anticorps
- MPDZ (Multiple PDZ Domain Protein (MPDZ))
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Épitope
- AA 388-480
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MPDZ est conjugé à/à la AbBy Fluor® 647
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Application
- Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain
- Homologie
- Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human MUPP1/MPDZ
- Isotype
- IgG
- Top Product
- Discover our top product MPDZ Anticorps primaire
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- Indications d'application
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- MPDZ (Multiple PDZ Domain Protein (MPDZ))
- Autre désignation
- MUPP1/MPDZ (MPDZ Produits)
- Synonymes
- anticorps HYC2, anticorps MUPP1, anticorps AI225843, anticorps B930003D11Rik, anticorps multiple PDZ domain crumbs cell polarity complex component, anticorps multiple PDZ domain protein, anticorps Multiple PDZ domain protein, anticorps inactivation-no-after-potential D protein, anticorps multiple pdz domain protein, putative, anticorps MPDZ, anticorps Mpdz, anticorps mpz-1, anticorps LOC5569990, anticorps Smp_168960
- Sujet
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Synonyms: MPDZ, Multi PDZ domain protein 1, Multi-PDZ domain protein 1, multiple PDZ domain protein, MPDZ_HUMAN.
Background: MPDZ is a 2,042 amino acid peripheral membrane protein that colocalizes with SR-2C on the apical membrane of epithelial choroid plexus cells. Expressed in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas, MPDZ causes clustering of SR-2C, a serotonin receptor, at the cell surface. MPDZ is member of the NMDAR signaling complex that is involved in regulating AMPAR potentiation and synaptic plasticity in excitatory synapses. As a tight junction protein in epithelial cells, MPDZ interacts with SSTR3, a G-protein-coupled receptor, to regulate transepithelial permeability in a pertussis toxin sensitive manner. MPDZ, along with Kir4.2, may form a complex with other proteins in the nephron and regulate ion transport. MPDZ contains one L27 domain and thirteen PDZ domains.
- Pathways
- Synaptic Membrane, Phototransduction
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