SLC6A7 anticorps (AA 151-260) (AbBy Fluor® 488)
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- Antigène Voir toutes SLC6A7 Anticorps
- SLC6A7 (Solute Carrier Family 6 (Neurotransmitter Transporter, L-Proline), Member 7 (SLC6A7))
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Épitope
- AA 151-260
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SLC6A7 est conjugé à/à la AbBy Fluor® 488
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human SLC6A7/PROT
- Isotype
- IgG
- Top Product
- Discover our top product SLC6A7 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- SLC6A7 (Solute Carrier Family 6 (Neurotransmitter Transporter, L-Proline), Member 7 (SLC6A7))
- Autre désignation
- SLC6A7/PROT (SLC6A7 Produits)
- Synonymes
- anticorps slc6a7, anticorps AW455934, anticorps PROT, anticorps Prot, anticorps solute carrier family 6 member 7, anticorps zgc:158225, anticorps solute carrier family 6 (neurotransmitter transporter, L-proline), member 7, anticorps SLC6A7, anticorps zgc:158225, anticorps slc6a7, anticorps Slc6a7
- Sujet
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Synonyms: SC6A7_HUMAN, Slc6a7, Sodium-dependent proline transporter, Solute carrier family 6 member 7.
Background: The GAT1 gene family includes sodium- and chloride-dependent plasma membrane transporters for neurotransmitters, metabolites and osmolites, which couple substrate flux to transmembrane electrochemical gradients. PROT (Sodium-dependent proline transporter), also known as Solute carrier family 6 member 7, is a 636 amino acid multi-pass membrane protein that is a GAT1 family member specifically expressed in regions of the brain. PROT terminates the action of proline by its high affinity sodium/chloride-dependent reuptake into pre-synaptic terminals. Enriched in glutamatergic synaptic terminals, it is likely that PROT plays an important role in excitatory events of neurotransmission. PROT-mediated proline uptake is inhibited by compounds such as benztropine, LP-403812 and Des-Tyr-Leu-enkephalin (GGFL). These inhibitors of proline uptake may lead to the development of therapeutic agents for certain neurologic disorders.
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