SHROOM2 anticorps (AA 701-850) (Biotin)

N° du produit ABIN1395343

Détail du produit anti-SHROOM2 anticorps (Biotin)

Antigène: SHROOM2 (Shroom Family Member 2 (SHROOM2))

Épitope: AA 701-850

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHROOM2 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human APXL

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur SHROOM2

Antigène: SHROOM2 (Shroom Family Member 2 (SHROOM2))

Autre désignation: APXL (SHROOM2 Produits)

Synonymes: anticorps SHROOM2, anticorps APXL, anticorps apxl, anticorps shrm2, anticorps HSAPXL, anticorps 4832440C16, anticorps Apxl, anticorps C630003H05Rik, anticorps Shrm2, anticorps shroom family member 2, anticorps SHROOM2, anticorps shroom2, anticorps Shroom2

Sujet:

Synonyms: Apical like protein, Apical like protein APXL protein, apical protein of Xenopus-like, Apical protein Xenopus laevis like, apical protein, Xenopus laevis-like, apical protein-like, apical protein-like Xenopus laevis, Apical-like protein, APX homolog of Xenopus, C630003H05Rik, DKFZp781J074, FLJ39277, HSAPXL, Liver regeneration-related protein LRRG167, Protein Apxl, Protein Shroom2, Shrm2, SHRM2_HUMAN, SHROOM 2, Shroom family member 2, shroom2.

Background: APXL is a 1,616 amino acid protein that localizes to a variety of locations within the cell, including the cytoplasm, the cytoskeleton, the cell junction and the apical cell membrane. Containing one ASD1 domain, one ASD2 domain and one PDZ domain, APXL interacts with F-Actin and is thought to mediate endothelial cell morphology during cell spreading, possibly regulating melanosome biogenesis and inducing _ Tubulin redistribution. APXL is expressed in kidney, brain, lung, pancreas and placenta and is overexpressed in melanomas, suggesting a role in tumor transformation and metastasis. The gene encoding APXL maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.

Pathways: Cell-Cell Junction Organization, Asymmetric Protein Localization