DLGAP2 anticorps (AA 251-360) (Biotin)

N° du produit ABIN1395391

Détail du produit anti-DLGAP2 anticorps (Biotin)

Antigène: DLGAP2 (Discs, Large (Drosophila) Homolog-Associated Protein 2 (DLGAP2))

Épitope: AA 251-360

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLGAP2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Rat

Homologie: Mouse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SAPAP2/DLGAP2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur DLGAP2

Antigène: DLGAP2 (Discs, Large (Drosophila) Homolog-Associated Protein 2 (DLGAP2))

Autre désignation: SAPAP2/DLGAP2 (DLGAP2 Produits)

Synonymes: anticorps PSD-95, anticorps DAP2, anticorps SAPAP2, anticorps 6430596N04Rik, anticorps Sapap2, anticorps DLG associated protein 2, anticorps disks large-associated protein 2, anticorps discs, large (Drosophila) homolog-associated protein 2a, anticorps discs, large (Drosophila) homolog-associated protein 2, anticorps DLGAP2, anticorps LOC463960, anticorps dlgap2a, anticorps LOC100447448, anticorps Dlgap2

Sujet:

Synonyms: DAP-2, DAP2, Discs large Drosophila homolog associated protein 2, Discs large homolog associated protein 2, Disks large-associated protein 2, Dlgap2, DLGP2_HUMAN, PSD-95/SAP90-binding protein 2, SAP90/PSD-95-associated protein 2, SAPAP2, hide.

Background: A guanylate kinase is a phosphotransferase that produces ADP and GDP from the substrates ATP and GMP. SAPAP2, also known as DAP-2 (Disks large-associated protein 2) and PSD-95/SAP90-binding protein 2, is a 1054 amino acid protein that localizes to the postsynaptic membrane of neuronal cells of the brain and kidney. SAPAP2 likely acts as a signaling molecule which interacts with the human genes DLG1 and DLG4/PSD-95. The gene encoding SAPAP2, DLGAP2, maps to human chromosome 8. Consisting of nearly 146 million base pairs, chromosome 8 encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8.