LRFN1 anticorps (AA 181-290) (AbBy Fluor® 555)
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- Antigène Voir toutes LRFN1 Anticorps
- LRFN1 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 1 (LRFN1))
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Épitope
- AA 181-290
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LRFN1 est conjugé à/à la AbBy Fluor® 555
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human LRFN1
- Isotype
- IgG
- Top Product
- Discover our top product LRFN1 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- LRFN1 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 1 (LRFN1))
- Autre désignation
- LRFN1 (LRFN1 Produits)
- Synonymes
- anticorps SALM2, anticorps BC004018, anticorps Semo1, anticorps leucine rich repeat and fibronectin type III domain containing 1, anticorps LRFN1, anticorps Lrfn1
- Sujet
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Synonyms: Leucine rich repeat and fibronectin type III domain containing 1, Leucine rich repeat and fibronectin type III domain containing protein 1, Leucine-rich repeat and fibronectin type III domain-containing protein 1, LRFN 1, lrfn1, LRFN1_HUMAN, SALM 2, SALM2, Synaptic adhesion like molecule 2, Synaptic adhesion-like molecule 2.
Background: LRFN1 is a 771 amino acid single-pass type I membrane protein that belongs to the LRFN family. Containing a fibronectin type-III domain, an Ig-like (immunoglobulin-like) domain, a LRRCT domain, a LRRNT domain and seven LRR (leucine-rich) repeats, LRFN1 is thought to promote neurite outgrowth in hippocampal neurons and is involved in the regulation and maintenance of excitatory synapses. LRFN1 forms heteromeric complexes with LRFN2, LRFN3, LFRN4 and LFRN5, but does not have the ability to form homomeric complexes across cell junctions of adjacent cells like other LRFN family members. The PDZ-binding motif of LRFN1 is required for neurite outgrowth promotion and for SAP 97-, NE-dlg- and PSD-95-binding. LRFN1 is encoded by a gene located on human chromosome 19q13.2 and mouse chromosome 7 A3.
- Pathways
- Synaptic Membrane
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