UTF1 anticorps (AA 101-170) (Biotin)

N° du produit ABIN1395787

Détail du produit anti-UTF1 anticorps (Biotin)

Antigène: UTF1 (Undifferentiated Embryonic Cell Transcription Factor 1 (UTF1))

Épitope: AA 101-170

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UTF1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Cow

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human UTF1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur UTF1

Antigène: UTF1 (Undifferentiated Embryonic Cell Transcription Factor 1 (UTF1))

Autre désignation: UTF1 (UTF1 Produits)

Synonymes: anticorps AI505934, anticorps undifferentiated embryonic cell transcription factor 1, anticorps UTF1, anticorps Utf1, anticorps LOC616910

Sujet:

Synonyms: hUTF 1, hUTF1, Undferentiated embryonic cell transcription factor 1, UTF 1, UTF1, UTF1_HUMAN.

Background: UTF1 is a 341 amino acid protein that localizes to the nucleus and is subject to post-translational phosphorylation. Associating with the TFIID complex via an interaction with the TATA box binding protein (TFIID), UTF1 binds to the N-terminal region of ATF-2 and, via this binding, acts as a transcriptional coactivator of ATF-2, thereby enhancing transcriptional activity. Human UTF1 shares 64 % homology with its mouse counterpart, suggesting a similar role between species. The gene encoding UTF1 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5 % of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman?s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

ID gène: 8433