ZNF281 anticorps (AbBy Fluor® 488)

N° du produit ABIN1395790

Détail du produit anti-ZNF281 anticorps (AbBy Fluor® 488)

Antigène: ZNF281 (Zinc Finger Protein 281 (ZNF281))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF281 est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB)

Réactivité croisée: Humain

Homologie: Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ZNF281

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ZNF281

Antigène: ZNF281 (Zinc Finger Protein 281 (ZNF281))

Autre désignation: Znf281 (ZNF281 Produits)

Synonymes: anticorps ZNF281, anticorps zbp-99, anticorps znp-99, anticorps ZBP-99, anticorps ZNP-99, anticorps Znf281, anticorps zinc finger protein 281, anticorps ZNF281, anticorps znf281, anticorps Zfp281

Sujet:

Synonyms: Zfp281, GC box binding zinc finger protein 1, GC-box-binding zinc finger protein 1, GZP1, Transcription factor ZBP-99, ZBP 99, ZBP99, zfp281, Zinc finger DNA binding protein 99, Zinc finger DNA-binding protein 99, Zinc Finger Protein 281, ZN281_HUMAN, ZNF281, ZNP 99, ZNP 99 transcription factor, ZNP99.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF281, also known as GC-box-binding zinc finger protein 1, ZBP-99 or ZNP-99 (zinc finger DNA-binding protein 99), is a zinc finger protein that belongs to the Kr_ppel C2H2-type zinc finger protein family. It is expressed ubiquitously at low levels with predominant expression in kidney, liver, lymphocytes and placenta. ZNF281 localizes to the nucleus and contains four C2H2-type zinc fingers. ZNF281 plays a role in repressing the transcription of a variety of genes including Gastrin and ODC (ornithine decarboxylase). In particular, ZNF281 functions by binding to the G-rich box in the enhancer region of the gene. Upon DNA damage, ZNF281 may become phosphorylated by Atm or ATR.

ID gène: 23528

Pathways: Embryonic Body Morphogenesis