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LIG4 anticorps (AA 51-150) (Biotin)

LIG4 Reactivité: Humain WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1396062
  • Antigène Voir toutes LIG4 Anticorps
    LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))
    Épitope
    • 14
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reactivité
    • 60
    • 11
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 58
    • 2
    Lapin
    Clonalité
    • 51
    • 9
    Polyclonal
    Conjugué
    • 26
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LIG4 est conjugé à/à la Biotin
    Application
    • 33
    • 13
    • 13
    • 13
    • 12
    • 9
    • 8
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human DNA Ligase IV
    Isotype
    IgG
    Top Product
    Discover our top product LIG4 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))
    Autre désignation
    DNA Ligase IV/LIG4 (LIG4 Produits)
    Synonymes
    anticorps zgc:165595, anticorps lig4, anticorps DNA LIGASE IV, anticorps LIG4, anticorps lig4-A, anticorps 5830471N16Rik, anticorps tiny, anticorps DNL4, anticorps ligase IV, DNA, ATP-dependent, anticorps DNA ligase 4, anticorps ATP-dependent DNA ligase implicated in dsDNA break repair via nonhomologous end-joining, anticorps DNA ligase IV, anticorps ligase IV, DNA, ATP-dependent L homeolog, anticorps lig4, anticorps LIG4, anticorps LOC100212302, anticorps CpipJ_CPIJ005161, anticorps PTRG_09982, anticorps MCYG_05151, anticorps LOC657210, anticorps ATLIG4, anticorps lig4.L, anticorps Lig4
    Sujet

    Synonyms: LIG4S, DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4, LIG4

    Background: Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

    ID gène
    3981
    UniProt
    P49917
    Pathways
    Réparation de l'ADN, Production of Molecular Mediator of Immune Response
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