MLC1 anticorps (AA 321-377) (AbBy Fluor® 488)

N° du produit ABIN1397899

Détail du produit anti-MLC1 anticorps (AbBy Fluor® 488)

Antigène: MLC1

Épitope: AA 321-377

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLC1 est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MLC1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MLC1

Antigène: MLC1

Abstract: MLC1 Produits

Synonymes: anticorps LVM, anticorps MLC, anticorps VL, anticorps AW048630, anticorps BB074274, anticorps Kiaa0027-hp, anticorps WKL1, anticorps mKIAA0027, anticorps si:ch211-192n14.1, anticorps megalencephalic leukoencephalopathy with subcortical cysts 1, anticorps megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human), anticorps MLC1, anticorps Mlc1, anticorps mlc1

Sujet:

Synonyms: KIAA0027, LVM, Megalencephalic leukoencephalopathy with subcortical cysts 1, Membrane protein MLC1, MLC, MLC-1, MLC1_HUMAN, VL, WKL1.

Background: MLC1 is a 377 amino acid multi-pass membrane protein that may serve as a non-selective neuronal cation channel in brain. Mutant MLC1 proteins that show impaired folding have been corrected in vitro with the addition of a Ca(2+)-ATPase inhibitor, curcumin. Mutations in the gene encoding MLC1 is the cause of megalencephalic leukoencephalopathy with subcortical cysts, also known as van der Knaap disease, a rare syndrome characterized early in life by progressive brain destruction causing mental retardation and incoordination. Single nucleotide polymorphisms within the MLC1 gene may be associated with periodic catatonia, but there seems to be conflicting evidence on whether or not the gene is implicated in general schizophrenia.

ID gène: 23209

UniProt: Q15049