CTDSPL anticorps (AA 175-276) (AbBy Fluor® 350)

N° du produit ABIN1398009

Détail du produit anti-CTDSPL anticorps (AbBy Fluor® 350)

Antigène: CTDSPL (CTD Small Phosphatase-Like Protein (CTDSPL))

Épitope: AA 175-276

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTDSPL est conjugé à/à la AbBy Fluor® 350

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris

Homologie: Rat,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CTDSPL

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CTDSPL

Antigène: CTDSPL (CTD Small Phosphatase-Like Protein (CTDSPL))

Autre désignation: CTDSPL (CTDSPL Produits)

Sujet:

Synonyms: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3, CTD small phosphatase-like protein, CTDSL_HUMAN, CTDSP-like, Ctdspl, hYA22, N-like protein, NLI-interacting factor 1, Nuclear LIM interactor-interacting factor 1, Protein YA22, RBSP3, SCP3, Small C-terminal domain phosphatase 3, Small CTD phosphatase 3.

Background: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

ID gène: 10217