DIRC2 anticorps (AA 51-150) (AbBy Fluor® 488)
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- Antigène Voir toutes DIRC2 Anticorps
- DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))
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Épitope
- AA 51-150
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Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DIRC2 est conjugé à/à la AbBy Fluor® 488
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Rat
- Homologie
- Mouse,Dog,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human DIRC2
- Isotype
- IgG
- Top Product
- Discover our top product DIRC2 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))
- Autre désignation
- DIRC2 (DIRC2 Produits)
- Synonymes
- anticorps MGC80843, anticorps zgc:92095, anticorps rcc4, anticorps MGC69320, anticorps RCC4, anticorps disrupted in renal carcinoma 2, anticorps disrupted in renal carcinoma 2 L homeolog, anticorps disrupted in renal carcinoma 2 (human), anticorps DIRC2, anticorps dirc2.L, anticorps dirc2, anticorps Dirc2
- Sujet
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Synonyms: Disrupted in renal carcinoma protein 2, DIRC 2, Disrupted in renal cancer protein 2, Disrupted in renal carcinoma 2, FLJ14784, NP_116228, RCC 4, RCC4, Renal cell carcinoma 4, DIRC2_HUMAN.
Background: Belonging to the major facilitator superfamily, DIRC2 (disrupted in renal carcinoma protein 2) is a 478 amino acid multi-pass membrane protein that is primarily expressed in kidney proximal tubular cells. The genes encoding DIRC2 and DIRC3 are located at a translocation breakpoint which occurs frequently in individuals affected by familial renal cell carcinoma. Fusion transcripts that result from these translocations may affect normal protein function. This evidence suggests that, due to its chromosomal location, deregulation of the DIRC2 gene may cause haploinsufficiency and therefore result in the onset of tumor growth. There are two isoforms of DIRC2 which are produced as a result of alternative splicing events.
- ID gène
- 84925
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