UBE2J2 anticorps (AA 1-100) (Biotin)

N° du produit ABIN1398757

Détail du produit anti-UBE2J2 anticorps (Biotin)

Antigène: UBE2J2 (Ubiquitin-Conjugating Enzyme E2, J2 (UBE2J2))

Épitope: AA 1-100

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2J2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human UBE2J2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur UBE2J2

Antigène: UBE2J2 (Ubiquitin-Conjugating Enzyme E2, J2 (UBE2J2))

Autre désignation: UBE2J2 (UBE2J2 Produits)

Synonymes: anticorps NCUBE-2, anticorps NCUBE2, anticorps PRO2121, anticorps 1200007B18Rik, anticorps 2400008G19Rik, anticorps 5730472G04Rik, anticorps AL022923, anticorps Ubc6, anticorps Ubc6p, anticorps zgc:162164, anticorps ubiquitin conjugating enzyme E2 J2, anticorps ubiquitin-conjugating enzyme E2J 2, anticorps ubiquitin-conjugating enzyme E2, J2, anticorps ubiquitin-conjugating enzyme E2 J2, anticorps ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast), anticorps ubiquitin conjugating enzyme E2 J2 L homeolog, anticorps UBE2J2, anticorps Ube2j2, anticorps LOC5574000, anticorps CpipJ_CPIJ008956, anticorps ube2j2, anticorps uce2, anticorps ube2j2.L, anticorps LOC100067387

Sujet:

Synonyms: NCUBE-2, NCUBE2, Non-canonical ubiquitin-conjugating enzyme 2, UB2J2_HUMAN, UBC6, UBC6 homolog, ube2j2, Ubiquitin-conjugating enzyme E2 J2.

Background: Ubiquitination is an important molecular mechanism by which abnormal or short-lived proteins are targeted for degradation by the concerted efforts of at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2J2 (Ubiquitin-conjugating enzyme E2 J2), also known as NCUBE2 (Non-canonical ubiquitin-conjugating enzyme 2), is a 259 amino acid single pass type IV membrane protein that that belongs to the E2 ubiquitin-conjugating enzyme family and is involved in protein degradation. Localized to the membrane of the endoplasmic reticulum (ER), UBE2J2 catalyzes the attachment of ubiquitin to misfolded membrane proteins, thereby targeting them for proteasomal destruction. This ATP-dependent reaction yields AMP, a diphosphate and a ubiquitin-tagged protein and may be a method of quality control within the ER. Two isoforms of UBE2J2 exist due to alternative splicing events.

ID gène: 118424