APLP1 anticorps (AA 1-100) (Biotin)

N° du produit ABIN1399249

Détail du produit anti-APLP1 anticorps (Biotin)

Antigène: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Épitope: AA 1-100

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APLP1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human APLP1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur APLP1

Antigène: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Autre désignation: APLP1 (APLP1 Produits)

Sujet:

Synonyms: AMYLOID BETA A4 PRECURSOR-LIKE PROTEIN 1, AMYLOID PRECURSOR-LIKE PROTEIN, Amyloid-like protein 1 precursor, APLP 1, APLP, APLP-1, Aplp1, APLP1_HUMAN, C30.

Background: May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I.The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis.

ID gène: 333

Pathways: cAMP Metabolic Process