OSTM1 anticorps (AA 21-120) (AbBy Fluor® 350)
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- Antigène Voir toutes OSTM1 Anticorps
- OSTM1 (Osteopetrosis Associated Transmembrane Protein 1 (OSTM1))
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Épitope
- AA 21-120
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp OSTM1 est conjugé à/à la AbBy Fluor® 350
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Réactivité croisée
- Humain, Souris, Rat
- Homologie
- Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human OSTM1
- Isotype
- IgG
- Top Product
- Discover our top product OSTM1 Anticorps primaire
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- Indications d'application
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- OSTM1 (Osteopetrosis Associated Transmembrane Protein 1 (OSTM1))
- Autre désignation
- OSTM1 (OSTM1 Produits)
- Synonymes
- anticorps MGC145644, anticorps si:ch73-257c13.3, anticorps GIPN, anticorps GL, anticorps OPTB5, anticorps 1200002H13Rik, anticorps HSPC019, anticorps gl, anticorps Gipn, anticorps OSTM1, anticorps osteopetrosis associated transmembrane protein 1, anticorps OSTM1, anticorps ostm1, anticorps Ostm1
- Sujet
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Synonyms: GL, GIPN, OPTB5, HSPC019, Osteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit, OSTM1, UNQ6098/PRO21201
Background: OSTM1 (osteopetrosis associated transmembrane protein 1), also known as gl (gray-lethal) or HSPC019, is a 338 amino acid single-pass type I membrane protein that is expressed primarily in osteoclasts and melanocytes as well as brain, kidney and spleen. Bone autosomal recessive osteopetrosis (ARO) is the most severe form of hereditary bone disease whose cellular basis is in the osteoclast and is characterized by abnormally dense bone, due to defective resorption of immature bone. ARO is suggested to be caused by mutations in the OSTM1 gene. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. Defects in the OSTM1 gene are also the cause of the spontaneous gl mutant, which is responsible for a coat color defect in mice.
- ID gène
- 28962
- UniProt
- Q86WC4
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