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OSTM1 anticorps (AA 21-120) (FITC)

OSTM1 Reactivité: Humain, Rat, Souris WB, FACS, IF (p), IF (cc) Hôte: Lapin Polyclonal FITC
N° du produit ABIN1399442
  • Antigène Voir toutes OSTM1 Anticorps
    OSTM1 (Osteopetrosis Associated Transmembrane Protein 1 (OSTM1))
    Épitope
    • 15
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    Reactivité
    • 37
    • 19
    • 19
    • 3
    Humain, Rat, Souris
    Hôte
    • 37
    • 1
    Lapin
    Clonalité
    • 37
    • 1
    Polyclonal
    Conjugué
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp OSTM1 est conjugé à/à la FITC
    Application
    • 38
    • 17
    • 16
    • 12
    • 12
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human OSTM1
    Isotype
    IgG
    Top Product
    Discover our top product OSTM1 Anticorps primaire
  • Indications d'application
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    OSTM1 (Osteopetrosis Associated Transmembrane Protein 1 (OSTM1))
    Autre désignation
    OSTM1 (OSTM1 Produits)
    Synonymes
    anticorps MGC145644, anticorps si:ch73-257c13.3, anticorps GIPN, anticorps GL, anticorps OPTB5, anticorps 1200002H13Rik, anticorps HSPC019, anticorps gl, anticorps Gipn, anticorps OSTM1, anticorps osteopetrosis associated transmembrane protein 1, anticorps OSTM1, anticorps ostm1, anticorps Ostm1
    Sujet

    Synonyms: GL, GIPN, OPTB5, HSPC019, Osteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit, OSTM1, UNQ6098/PRO21201

    Background: OSTM1 (osteopetrosis associated transmembrane protein 1), also known as gl (gray-lethal) or HSPC019, is a 338 amino acid single-pass type I membrane protein that is expressed primarily in osteoclasts and melanocytes as well as brain, kidney and spleen. Bone autosomal recessive osteopetrosis (ARO) is the most severe form of hereditary bone disease whose cellular basis is in the osteoclast and is characterized by abnormally dense bone, due to defective resorption of immature bone. ARO is suggested to be caused by mutations in the OSTM1 gene. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. Defects in the OSTM1 gene are also the cause of the spontaneous gl mutant, which is responsible for a coat color defect in mice.

    ID gène
    28962
    UniProt
    Q86WC4
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