C9ORF72 anticorps (AA 391-481) (Biotin)

N° du produit ABIN1399939

Détail du produit anti-C9ORF72 anticorps (Biotin)

Antigène: C9ORF72 (Chromosome 9 Open Reading Frame 72 (C9ORF72))

Épitope: AA 391-481

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C9ORF72 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human C9orf72

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur C9ORF72

Antigène: C9ORF72 (Chromosome 9 Open Reading Frame 72 (C9ORF72))

Autre désignation: C9orf72 (C9ORF72 Produits)

Synonymes: anticorps CZH9orf72, anticorps ALSFTD, anticorps FTDALS, anticorps AI840585, anticorps c9orf72, anticorps chromosome Z C9orf72 homolog, anticorps chromosome 9 open reading frame 72, anticorps RIKEN cDNA 3110043O21 gene, anticorps similar to RIKEN cDNA 3110043O21, anticorps chromosome 9 open reading frame 72 L homeolog, anticorps CZH9orf72, anticorps C9orf72, anticorps 3110043O21Rik, anticorps RGD1359108, anticorps c9orf72.L

Sujet:

Synonyms: ALSFTD, FTDALS, Protein C9orf72, C9orf72

Background: Chromosome 9 consists of about 145 million bases and 4 % of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The C9orf72 gene product has been provisionally designated C9orf72 pending further characterization. There are two isoforms of C9orf72 that are produced as a result of alternative splicing events.

ID gène: 203228

UniProt: Q96LT7