PDZD4 anticorps (AbBy Fluor® 350)

N° du produit ABIN1400481

Détail du produit anti-PDZD4 anticorps (AbBy Fluor® 350)

Antigène: PDZD4 (PDZ Domain Containing 4 (PDZD4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDZD4 est conjugé à/à la AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PDZK4

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PDZD4

Antigène: PDZD4 (PDZ Domain Containing 4 (PDZD4))

Autre désignation: PDZK4 (PDZD4 Produits)

Synonymes: anticorps LU1, anticorps PDZK4, anticorps PDZRN4L, anticorps B230341P03, anticorps D130075J17Rik, anticorps Kiaa1444-hp, anticorps Pdzk4, anticorps Pdzrnk4l, anticorps Xlu, anticorps PDZ domain containing 4, anticorps PDZD4, anticorps Pdzd4

Sujet:

Synonyms: FERM and PDZ domain containing protein 2, PDZ domain containing protein 4, PDZ domain containing protein 5C, PDZ domain containing 4 PDZD5C, PDZK4, PDZK5C,FRPD2_HUMAN.

Background: PDZK4, also known as PDZRN4L (PDZ domain-containing RING finger protein 4-like protein) or LU1, is a 769 amino acid coiled-coil protein that contains one PDZ (DHR) domain. Encoded by a gene that maps to human chromosome Xq28, PDZK4 is conserved in dog, cow, mouse, rat and zebrafish. PDZK4 localizes to cytoplasm and is expressed specifically in adult and fetal brain. PDZK4 functions as an oncogene and is up-regulated in synovial carcinomas. Treatment of synovial sarcoma cells with small interfering RNA (siRNA) inhibits PDZK4 expression, resulting in tumor-cell growth suppression, suggesting that inappropriate expression of PDZK4 may play a role synovial sarcoma cell proliferation.The exact function of FRMPD2 is unknown. The protein contains a FERM domain: such structures are often involved in signal transduction pathways. Alternatively spliced transcript variants encoding different isoforms have been identified.

ID gène: 143162

UniProt: Q68DX3