DIS3L anticorps (AbBy Fluor® 350)
-
- Antigène Voir toutes DIS3L Anticorps
- DIS3L (DIS3-Like Exonuclease 1 (DIS3L))
- Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp DIS3L est conjugé à/à la AbBy Fluor® 350
-
Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human DIS3L
- Isotype
- IgG
- Top Product
- Discover our top product DIS3L Anticorps primaire
-
-
- Indications d'application
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- DIS3L (DIS3-Like Exonuclease 1 (DIS3L))
- Autre désignation
- DIS3L (DIS3L Produits)
- Synonymes
- anticorps DIS3L1, anticorps AV340375, anticorps RGD1308959, anticorps zgc:158615, anticorps DIS3 like exosome 3'-5' exoribonuclease, anticorps DIS3-like exosome 3'-5' exoribonuclease, anticorps DIS3L, anticorps dis3l, anticorps Dis3l, anticorps dis3l.L
- Sujet
-
Synonyms: DIS3 like exonuclease 1, DIS3 mitotic control homolog S. cerevisiae like, FLJ38088, KIAA1955, MGC4562, DI3L1_HUMAN.
Background: The exosome is a multi-protein complex composed of several highly conserved subunits, some of which are 3? to 5? exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich elements (AREs) in their untranslated 3? regions. DIS3, also known as RRP44, is a 958 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one PINc domain. Widely expressed with highest expression in testis, DIS3 functions as a component of the exosome exoribonuclease complex and is required for processing of 7S pre-RNA into a mature nuclear complex and, ultimately, for proper mitotic progression. Abnormal expression levels of DIS3 may be associated with colon cancer, suggesting a role for DIS3 in tumorigenesis. Multiple isoforms of DIS3 exist due to alternative splicing events.
- ID gène
- 115752
-