ZNRF3 anticorps (AA 120-165) (AbBy Fluor® 488)
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- Antigène Voir toutes ZNRF3 Anticorps
- ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
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Épitope
- AA 120-165
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ZNRF3 est conjugé à/à la AbBy Fluor® 488
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Application
- Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human ZNRF3
- Isotype
- IgG
- Top Product
- Discover our top product ZNRF3 Anticorps primaire
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- Indications d'application
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
- Autre désignation
- ZNRF3 (ZNRF3 Produits)
- Synonymes
- anticorps BK747E2.3, anticorps RNF203, anticorps AA591877, anticorps BC019575, anticorps Gm1167, anticorps zinc and ring finger 3, anticorps Znrf3, anticorps ZNRF3
- Sujet
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Synonyms: RNF203, BK747E2.3, E3 ubiquitin-protein ligase ZNRF3, RING finger protein 203, Zinc/RING finger protein 3, ZNRF3, KIAA1133
Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
- ID gène
- 84133
- UniProt
- Q9ULT6
- Pathways
- Signalisation WNT
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