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TRIM50 anticorps (AbBy Fluor® 647)

TRIM50 Reactivité: Humain, Rat, Souris WB, IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 647
N° du produit ABIN1401132
  • Antigène Voir toutes TRIM50 Anticorps
    TRIM50 (Tripartite Motif Containing 50 (TRIM50))
    Reactivité
    • 32
    • 16
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 32
    Lapin
    Clonalité
    • 32
    Polyclonal
    Conjugué
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TRIM50 est conjugé à/à la AbBy Fluor® 647
    Application
    • 32
    • 13
    • 13
    • 12
    • 12
    • 5
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human TRIM50
    Isotype
    IgG
    Top Product
    Discover our top product TRIM50 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    TRIM50 (Tripartite Motif Containing 50 (TRIM50))
    Autre désignation
    TRIM50 (TRIM50 Produits)
    Synonymes
    anticorps TRIM50A, anticorps tripartite motif containing 50, anticorps tripartite motif-containing 50, anticorps TRIM50, anticorps Trim50
    Sujet

    Synonyms: E3 ubiquitin ligase, E3 ubiquitin protein ligase TRIM50, TRIM50A, Tripartite mot containing protein 50, tripartite mot protein 50A, tripartite mot-containing 50A, TRI50_HUMAN.

    Background: The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM50 (tripartite motif containing 50), also known as TRIM50A or E3 ubiquitin-protein ligase TRIM50, is a 487 amino acid cytoplasmic protein that functions as an E3 ubiquitin-protein ligase. Containing one RING-type zinc finger, a B30.2/SPRY domain and a single B box-type zinc finger, TRIM50 belongs to the TRIM/RBCC family and undergoes post-translational auto-ubiquitination. TRIM50 exists as two alternatively spliced isoforms, designated TRIM50 alpha and TRIM50 beta, and has the ability to form dimers and trimers. The gene encoding TRIM50 maps to human chromosome 7, which houses over 1,000 genes, comprises nearly 5 % of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

    ID gène
    135892
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