VGLL2 anticorps (AbBy Fluor® 488)

N° du produit ABIN1401316

Détail du produit anti-VGLL2 anticorps (AbBy Fluor® 488)

Antigène: VGLL2 (Vestigial Like 2 (VGLL2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VGLL2 est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human VGLL2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur VGLL2

Antigène: VGLL2 (Vestigial Like 2 (VGLL2))

Autre désignation: VGLL2 (VGLL2 Produits)

Synonymes: anticorps VGL2, anticorps VITO1, anticorps vgll2a, anticorps MGC114146, anticorps zgc:114146, anticorps C130057C21Rik, anticorps VITO-1, anticorps Vito1, anticorps vgl-2, anticorps zgc:110098, anticorps vestigial like family member 2, anticorps vestigial-like family member 2, anticorps vestigial-like family member 2a, anticorps vestigial like family member 2 L homeolog, anticorps vestigial-like family member 2b, anticorps VGLL2, anticorps Vgll2, anticorps vgll2a, anticorps vgll2.L, anticorps vgll2b

Sujet:

Synonyms: Protein VITO1, Transcription cofactor vestigial like 2, Transcription cofactor vestigial like protein 2, Transcription cofactor vestigial-like protein 2, Vestigial like 2, Vestigial like 2 Drosophila, Vgl-2, VGL2, VGLL 2, Vgll2, VGLL2_HUMAN, VITO1.

Background: Vgl-2, also known as VITO-1, is a 317 amino acid protein that contains a domain through which it interacts with TEF-1, a protein that plays a role in controlling the expression of numerous genes. Specific to skeletal muscle, Vgl-2 is expressed highly in adult fast muscle and is expressed at lower levels in adult slow muscle and fetal skeletal muscle. During muscle differentiation, Vgl-2 mRNA levels increase and Vgl-2 translocates from the cytoplasm to the nucleus. Overexpression of Vgl-2 in MYOD-transfected 10T1/2 mouse embryonic fibroblasts increases expression of myosin heavy chain (MHC), which is a marker of terminal muscle differentiation. This evidence suggests that Vgl-2 is essential for muscle gene expression. There are two isoforms of Vgl-2 that are produced as a result of alternative splicing events.

ID gène: 245806