SH3RF2 anticorps (AbBy Fluor® 488)

N° du produit ABIN1401598

Détail du produit anti-SH3RF2 anticorps (AbBy Fluor® 488)

Antigène: SH3RF2 (SH3 Domain Containing Ring Finger 2 (SH3RF2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3RF2 est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RNF158

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SH3RF2

Antigène: SH3RF2 (SH3 Domain Containing Ring Finger 2 (SH3RF2))

Autre désignation: RNF158 (SH3RF2 Produits)

Synonymes: anticorps MGC81405, anticorps SH3RF2, anticorps HEPP1, anticorps POSHER, anticorps PPP1R39, anticorps RNF158, anticorps 2310046K19, anticorps 9130023G24Rik, anticorps AI452083, anticorps Ppp1r39, anticorps Posh2, anticorps SH3 domain containing ring finger 2, anticorps SH3 domain containing ring finger 2 S homeolog, anticorps SH3RF2, anticorps sh3rf2.S, anticorps sh3rf2, anticorps Sh3rf2

Sujet:

Synonyms: Heart protein phosphatase 1-binding protein, HEPP1, Putative E3 ubiquitin protein ligase SH3RF2, Putative E3 ubiquitin-protein ligase SH3RF2, RING finger protein 158, SH3 domain containing RING finger protein 2, SH3 domain-containing RING finger protein 2, SH3R2_HUMAN, Sh3rf2.

Background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. SH3RF2 (SH3 domain containing ring finger 2), also known as RNF158, is a 729 amino acid protein with one RING-type zinc finger domain and three SH3 domains. Via its RING-type zinc finger domain, SH3RF2 binds an E2 ubiquitin-conjugating enzyme. This suggests that SH3RF2 functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation. Due to alternative splicing events, SH3RF2 is expressed as two different isoforms.

ID gène: 153769