STIL anticorps (Biotin)

N° du produit ABIN1401943

Détail du produit anti-STIL anticorps (Biotin)

Antigène: STIL (SCL/TAL1 Interrupting Locus (STIL))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STIL est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human STIL

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur STIL

Antigène: STIL (SCL/TAL1 Interrupting Locus (STIL))

Autre désignation: STIL (STIL Produits)

Synonymes: anticorps Sil, anticorps MCPH7, anticorps SIL, anticorps chunp6907, anticorps sill, anticorps zgc:110502, anticorps STIL, centriolar assembly protein, anticorps Scl/Tal1 interrupting locus, anticorps STIL, centriolar assembly protein L homeolog, anticorps scl/tal1 interrupting locus, anticorps Stil, anticorps STIL, anticorps stil.L, anticorps stil

Sujet:

Synonyms: MCPH7, SCL interrupting locus protein, SCL-interrupting locus protein, SCL/TAL1 interrupting locus, SIL, STIL, STIL_HUMAN, TAL 1 interrupting locus protein, TAL-1-interrupting locus protein.

Background: TAL1 disruption at 1p32, a common rearrangement in the T-cell acute lymphoblastic leukemia, usually results in the formation of a SCL interrupting locus (SIL)-TAL1 fusion product. SIL is an immediate early gene whose expression is associated with cell proliferation. The Sil protein exhibits ubiquitous expression in hematopoietic cell lines and tissues. However, Sil protein levels remain tightly regulated during the cell cycle, achieving peak levels in mitosis and diminishing on transition to G1 phase. Overexpression of Sil in primary adenocarcinomas predicts metastatic spread, especially in lung tumors with increased mitotic activity.

ID gène: 6491

Pathways: Tube Formation