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PSMA7 anticorps (AbBy Fluor® 555)

PSMA7 Reactivité: Humain, Souris, Rat WB, IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 555
N° du produit ABIN1402253
  • Antigène Voir toutes PSMA7 Anticorps
    PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
    Reactivité
    • 52
    • 32
    • 17
    • 1
    Humain, Souris, Rat
    Hôte
    • 44
    • 8
    Lapin
    Clonalité
    • 45
    • 7
    Polyclonal
    Conjugué
    • 24
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PSMA7 est conjugé à/à la AbBy Fluor® 555
    Application
    • 43
    • 17
    • 15
    • 12
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Proteasome 20S alpha 7
    Isotype
    IgG
    Top Product
    Discover our top product PSMA7 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
    Abstract
    PSMA7 Produits
    Synonymes
    anticorps C6, anticorps HSPC, anticorps RC6-1, anticorps XAPC7, anticorps C6-I, anticorps DDBDRAFT_0185059, anticorps DDBDRAFT_0217080, anticorps DDB_0185059, anticorps DDB_0217080, anticorps hspc, anticorps rc6-1, anticorps xapc7, anticorps psma7, anticorps psma4-B, anticorps proteasome subunit alpha 7, anticorps proteasome (prosome, macropain) subunit, alpha type 7, anticorps 20S proteasome subunit alpha-7, anticorps proteasome subunit alpha 7 S homeolog, anticorps proteasome subunit alpha 7 L homeolog, anticorps PSMA7, anticorps Psma7, anticorps psmA7, anticorps psma7, anticorps psma7.S, anticorps psma7.L
    Sujet

    Synonyms: C6 antibody HSPC, Proteasome prosome macropain subunit alpha type 7, Proteasome alpha 7 subunit, Proteasome subunit alpha 4, Proteasome subunit alpha type 7, Proteasome subunit alpha type-7, Proteasome subunit RC6 1, Proteasome subunit RC6-1, Proteasome subunit XAPC7, PSA7_HUMAN, PSMA7, RC6 1, XAPC7.

    Background: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH . The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.

    ID gène
    5688
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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