TRIM54 anticorps (Biotin)

N° du produit ABIN1402363

Détail du produit anti-TRIM54 anticorps (Biotin)

Antigène: TRIM54 (Tripartite Motif Containing 54 (TRIM54))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM54 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MURF3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur TRIM54

Antigène: TRIM54 (Tripartite Motif Containing 54 (TRIM54))

Autre désignation: MURF3 (TRIM54 Produits)

Synonymes: anticorps MGC80214, anticorps si:dkey-221h15.2, anticorps DKFZp468L1522, anticorps MURF, anticorps MURF-3, anticorps RNF30, anticorps muRF3, anticorps 4930486E09Rik, anticorps 4930566I02Rik, anticorps MuRF3, anticorps Rnf30, anticorps tripartite motif containing 54, anticorps tripartite motif containing 54 S homeolog, anticorps tripartite motif-containing 54, anticorps TRIM54, anticorps trim54.S, anticorps trim54, anticorps Trim54

Sujet:

Synonyms: MURF 3, MURF, MURF-3, MuRF3, Muscle specic RING finger protein 3, Muscle specic RING finger protein, Muscle specic RING finger protein homolog, Muscle-specic RING finger protein 3, Muscle-specic RING finger protein, Ring finger protein 30, RNF30, TRI54_HUMAN, TRIM 54, TRIM54, RNF28, Tripartite mot containing 54, tibody Tripartite mot-containing protein 54.

Background: MuRF1, is a nuclear protein that interacts with SMT3b and the large myofibrillar protein Titin. In muscle cells, MuRF2 (RFN29) regulates gene expression and protein turnover. It localizes to the cytoplasm, but under atrophic conditions it is detected in the nucleus. MuRF2 can form oligomers with various other proteins, including Titin and Myosin. MuRF3, also designated tripartite motif-containing 54 (TRIM54) or ring finger protein 30 (RNF30), interacts with tubulin and stabilizes microtubules duing myotube formation. It is a cytoplasmic protein the localizes to the Z-lines in skeletal muscles, while MuRF2 localizes to the sarcomeric M-band in cardiomyocytes. MuRF3 shares 77 % and 65 % sequence identity with MuRF1 and MuRF2, respectively. MuRF1-3 share a conserved N-terminal RING domain and zinc-binding B-box motif, and two coiled-coil dimerization motif boxes, in their central regions.

ID gène: 57159