MEF2B anticorps (AbBy Fluor® 488)
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- Antigène Voir toutes MEF2B Anticorps
- MEF2B (Myocyte Enhancer Factor 2B (MEF2B))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MEF2B est conjugé à/à la AbBy Fluor® 488
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human MEF2B
- Isotype
- IgG
- Top Product
- Discover our top product MEF2B Anticorps primaire
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- Indications d'application
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- MEF2B (Myocyte Enhancer Factor 2B (MEF2B))
- Autre désignation
- MEF2B (MEF2B Produits)
- Synonymes
- anticorps si:ch211-125m10.1, anticorps AI451606, anticorps RSRFR2, anticorps myocyte enhancer factor 2b, anticorps myocyte enhancer factor 2B, anticorps mef2b, anticorps MEF2B, anticorps Mef2b
- Sujet
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Synonyms: PRDM3, MADS box transcription enhancer factor 2, MDS1 EVI1, Mef2b, MEF2B_HUMAN, MEF-2B, myocyte enhancer factor 2B, myocyte specic enhancer factor 2B, Myocyte-specic enhancer factor 2B, RSRFR2, serum response factor like protein 2, Serum response factor-like protein 2, XMEF2.
Background: The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells, and muscle cells. Four family members, termed MEF-2A, -2B, -2C, and -2D, arise from alternatively spliced transcripts. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5, and MRF4, are one class of identified factors. The MEF-2 family represents a second class of DNA binding regulatory proteins. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.
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