MEF2B anticorps (Biotin)

N° du produit ABIN1402903

Détail du produit anti-MEF2B anticorps (Biotin)

Antigène: MEF2B (Myocyte Enhancer Factor 2B (MEF2B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEF2B est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MEF2B

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur MEF2B

Antigène: MEF2B (Myocyte Enhancer Factor 2B (MEF2B))

Autre désignation: MEF2B (MEF2B Produits)

Synonymes: anticorps si:ch211-125m10.1, anticorps AI451606, anticorps RSRFR2, anticorps myocyte enhancer factor 2b, anticorps myocyte enhancer factor 2B, anticorps mef2b, anticorps MEF2B, anticorps Mef2b

Sujet:

Synonyms: PRDM3, MADS box transcription enhancer factor 2, MDS1 EVI1, Mef2b, MEF2B_HUMAN, MEF-2B, myocyte enhancer factor 2B, myocyte specic enhancer factor 2B, Myocyte-specic enhancer factor 2B, RSRFR2, serum response factor like protein 2, Serum response factor-like protein 2, XMEF2.

Background: The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells, and muscle cells. Four family members, termed MEF-2A, -2B, -2C, and -2D, arise from alternatively spliced transcripts. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5, and MRF4, are one class of identified factors. The MEF-2 family represents a second class of DNA binding regulatory proteins. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.