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EPR1 anticorps (Biotin)

EPR1 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1403125
  • Antigène Voir toutes EPR1 Anticorps
    EPR1 (Early-Phytochrome-Responsive1 (EPR1))
    Reactivité
    Humain
    Hôte
    • 18
    Lapin
    Clonalité
    • 18
    Polyclonal
    Conjugué
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EPR1 est conjugé à/à la Biotin
    Application
    • 18
    • 13
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human EPR1
    Isotype
    IgG
    Top Product
    Discover our top product EPR1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    EPR1 (Early-Phytochrome-Responsive1 (EPR1))
    Autre désignation
    EPR1 (EPR1 Produits)
    Sujet

    Synonyms: Effector cell peptidase receptor 1, Effector cell protease receptor 1, EPR 1, EPR1, EPR-1.

    Background: Cellular receptors for blood proteases regulate chemotaxis, extracellular proteolysis, and growth behavior of normal and malignant cells. Effector cell protease receptor-1 (EPR1) is a receptor for the coagulation protease factor Xa. EPR1 is characterized by a cysteine-rich extracellular module, a single membrane-spanning domain, and a serine-rich cytoplasmic tail featuring at least 15 potential phosphorylation sites. EPR1 also contains 2 N-linked glycosylation sites, 4 O-linked glycosylation sites, and a chondroitin sulfate attachment site, which may provide anchoring for carbohydrate chains, EPR1 transfectants bind to factor Xa in a specific and saturable manner, and in the absence of factor V/Va promote prothrombin activation in a factor Xa concentration-dependent reaction. Activated platelets and megakaryocytes express EPR1. Both EPR1 and membrane-bound factor Va are thought to be required to mediate factor Xa binding to the activated platelet to form a functional prothrombinase complex.

    ID gène
    8475
    Pathways
    Apoptose, Cycle Cellulaire
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