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C17ORF77 anticorps (AbBy Fluor® 555)

C17ORF77 Reactivité: Humain WB, IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 555
N° du produit ABIN1403855
  • Antigène Tous les produits C17ORF77
    C17ORF77 (Chromosome 17 Open Reading Frame 77 (C17ORF77))
    Reactivité
    Humain
    Hôte
    • 16
    Lapin
    Clonalité
    • 16
    Polyclonal
    Conjugué
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp C17ORF77 est conjugé à/à la AbBy Fluor® 555
    Application
    • 16
    • 12
    • 3
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human C17orf77
    Isotype
    IgG
  • Indications d'application
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    C17ORF77 (Chromosome 17 Open Reading Frame 77 (C17ORF77))
    Autre désignation
    C17orf77 (C17ORF77 Produits)
    Synonymes
    anticorps chromosome 17 open reading frame 77, anticorps C17orf77
    Sujet

    Synonyms: chromosome 17 open reading frame 77, CQ077_HUMAN, hypothetical protein LOC146723, Uncharacterized protein C17orf77.

    Background: C17orf77 is a 243 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5 % of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

    ID gène
    146723
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