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C17orf59 anticorps (AbBy Fluor® 555)

C17ORF59 Reactivité: Humain, Souris, Rat WB, IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 555
N° du produit ABIN1404953
  • Antigène Tous les produits C17orf59 (C17ORF59)
    C17orf59 (C17ORF59) (Chromosome 17 Open Reading Frame 59 (C17ORF59))
    Reactivité
    • 32
    • 23
    • 15
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 32
    Lapin
    Clonalité
    • 32
    Polyclonal
    Conjugué
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp C17orf59 est conjugé à/à la AbBy Fluor® 555
    Application
    • 31
    • 12
    • 12
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human C17orf59
    Isotype
    IgG
  • Indications d'application
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    C17orf59 (C17ORF59) (Chromosome 17 Open Reading Frame 59 (C17ORF59))
    Autre désignation
    C17orf59 (C17ORF59 Produits)
    Synonymes
    anticorps PRO2472, anticorps C17orf59, anticorps BLOC-1 related complex subunit 6, anticorps BORCS6, anticorps Borcs6
    Sujet

    Synonyms: Chromosome 17 open reading frame 59, CQ059_HUMAN, FLJ20014, PRO2472, Uncharacterized protein C17orf59.

    Background: C17orf59 is a 357 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5 % of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

    ID gène
    54785
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