C9 anticorps (AA 161-260) (HRP)

N° du produit ABIN1407704

Détail du produit anti-C9 anticorps (HRP)

Antigène: C9 (Complement Component C9 (C9))

Épitope: AA 161-260

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C9 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Complement component C9a

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur C9

Antigène: C9 (Complement Component C9 (C9))

Autre désignation: C9a/C9 (C9 Produits)

Synonymes: anticorps LOC100037951, anticorps LOC100136130, anticorps c9, anticorps wu:fb60b05, anticorps wu:fd50e04, anticorps zgc:112272, anticorps complement C9, anticorps complement component 9, anticorps complement component 9 L homeolog, anticorps C9, anticorps c9, anticorps c9.L

Sujet:

Synonyms: C9a, C9 deficiency, C9 deficiency with dermatomyositis, CO9_HUMAN, Complement component 9, Complement component 9 deficiency, Complement component C9a, Complement component C9a, C9.

Background: C9 is a plasma protein synthesized in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerization of 12-18 C9 Molecules. These polymerized C9 Molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell.

Pathways: Système du Complément