Semaphorin 6C anticorps (AA 256-305) (HRP)

N° du produit ABIN1409432

Détail du produit anti-Semaphorin 6C anticorps (HRP)

Antigène: Semaphorin 6C (SEMA6C) (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6C (SEMA6C))

Épitope: AA 256-305

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Semaphorin 6C est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SEMA6C

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Semaphorin 6C

Antigène: Semaphorin 6C (SEMA6C) (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6C (SEMA6C))

Autre désignation: SEMA6C (SEMA6C Produits)

Synonymes: anticorps SEMAY, anticorps m-SemaY, anticorps m-SemaY2, anticorps Semay, anticorps mKIAA1869, anticorps semaphorin 6C, anticorps sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C, anticorps SEMA6C, anticorps Sema6c

Sujet:

Synonyms: KIAA1869, m Sema Y, m Sema Y2, sema domain, transmembrane domain TM, and cytoplasmic domain, semaphorin 6C, Sema Y antibody Semaphorin 6C [Precursor], Semaphorin Y, SEMAY, SEM6C_HUMAN.

Background: Semaphorins are a family of cell surface and secreted proteins involved in neural development that are conserved from insects to humans. Members of this family are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular semaphorin? domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. The transmembrane semaphorins are characterized by an additional 80 amino acid transmembrane domain and an 80-110 amino acid cytoplasmic domain. SEMA6C, also known as SEMA Y, is a transmembrane protein expressed in fetal brain and adult skeletal muscle. Three isoforms of this semaphorin exist due to alternative splicing: SEMA6C 1, SEMA6C 2 and SEMA6C 3. The extracellular domain of SEMA6C induces growth cone collapse of dorsal root ganglion and plays a role in generation or stability of entorhino-hippocampal synapses.